Publications

Publications from work done at Georgia Tech. Name underlined when corresponding author

  1. Khodaverdian, V.; Tapadar, S.; MacDonald, I. A.; Xu, Y.; Ho, P-Y.; Bridges, A.; Rajpurohit, P.; Sanghani, B. A.; Fan, Y.; Thangaraju, M.; Hathaway, N. A.; Oyelere, A. K. Deferiprone: Pan-selective Histone Lysine Demethylase Inhibition Activity and Structure Activity Relationship Study. Scientific Reports 2019, 9:4802 | https://doi.org/10.1038/s41598-019-39214-1.
  2. Oyebode, O. T.; Owumi, S. E.; Oyelere, A. K.; Olorunsogo, O. O. Calliandra portoricensis Benth exhibits anticancer effects via alteration of Bax/Bcl-2 ratio and growth arrest in prostate LNCaP cells. Ethnopharmacol. 2019, 233, 64-72.
  3. Story, S.; Skriba, M. J.; Maiti, K.; Ranjan, N.; Degtyareva, N. N.; Green, K. D.; Khodaverdian, V.; Oyelere, A. K.; Garneau-Tsodikova, S.; Arya, D. P. Synthesis, antimicrobial activity, attenuation of aminoglycoside resistance in MRSA, and ribosomal A-site binding of pyrene-neomycin conjugates. J. Med. Chem. 2019, 163, 381-393.
  4. Xu, J.; Jia, Y-F.; Tapadar, S.; Weaver, J. D.; Raji, I. O.; Pithadia, D. J.; Javeed, N.; García, A. J.; Choi, D-S.; Matveyenko, A. V.; Oyelere, A. K.; Shin, C. H. Inhibition of TBK1/IKKε Promotes Regeneration of Pancreatic β-cells. Scientific Reports 2018, 8:15587 | DOI:10.1038/s41598-018-33875-0.
  5. George, A.; Raji, I.; Cinar, B.; Kucuk, O.; Oyelere, A. K. Design, synthesis and evaluation of antiproliferative activity of hydantoin-derived antiandrogen-genistein conjugates. Med. Chem. 2018, 26, 1481-1487.
  6. Pavlova, ; Parks, J. M.; Oyelere, A. K.; Gumbart, J. C. Towards a rational design of macrolide antibiotics to combat resistance. Chem Biol Drug Des 2017, 90, 641-652. doi:10.1111/cbdd.13004 [Editor’s choice]
  7. Degtyareva, N.; Gong, C.; Story, S.; Levinson, N. S.; Oyelere, A. K.; Green, K. D.; Garneau-Tsodikova, S.; Arya, D. P. Antimicrobial Activity, AME Resistance, and A‑Site Binding Studies of 2-Anthraquinone-Neomycin Conjugates. ACS Infect Dis. 2017, 3, 206-215. doi: 10.1021/acsinfecdis.6b00176.
  8. Raji, I.; Ahluwalia, K.; Oyelere, A. K. Design, synthesis and evaluation of antiproliferative activity of melanoma-targeted histone deacetylase inhibitors. Med. Chem. Lett. 2017, 27, 744–749.
  9. Raji, I; Yadudu, F.; Janeira, E.; Fathi, S.; Szymczak, L.; Kornacki, J. R.; Komatsu, K.; Li, J-D.; Mrksich, M.; Oyelere, A. K. Bifunctional Conjugates with Potent Inhibitory Activity Towards Cyclooxygenase and Histone Deacetylase. Med. Chem. 2017, 25, 1202–1218.
  10. Fathi, S.; Oyelere, A. K. Liposomal Drug Delivery Systems for Targeted Cancer Therapy. Is active targeting the best choice? Future Med. Chem. 2016, 8, 2091-2112 (doi: 10.4155/fmc-2016-0135).
  11. Tapadar, S.; Fathi, S.; Raji, I.; Omesiete, W.; Kornacki, J. R.; Mwakwari, S. C.; Miyata, M.; Mitsutake, K.; Li, J.-D.; Mrksich, M.; Oyelere, A. K. A structure–activity relationship of non-peptide macrocyclic histone deacetylase inhibitors and their anti-proliferative and anti-inflammatory activities. Med. Chem. 2015, 23, 7543–7564.
  12. Washington, A. Z.; Tapadar, S.; George, A.; Oyelere, A. K. Exploiting Translational Stalling Peptides in an Effort to Extend Azithromycin Interaction Within the Prokaryotic Ribosome Nascent Peptide Exit Tunnel. Med. Chem. 2015, 23, 5198-5209.
  13. Owumi, S. E.; Oyelere, A. K. Determination of metal ion contents of two antiemetic clays use in Geophagy. Toxicology Reports 2015, 2, 928–932.
  14. Sodji, Q.; Kornacki, J. R; McDonald, J.; Mrksich, M.; Oyelere, A. K. Design and Structure Activity Relationship of Tumor-Homing Histone Deacetylase Inhibitors Conjugated to Folic and Pteroic Acids. J. Med. Chem. 2015, 96, 340-359.
  15. Sodji, Q.; Kornacki, J. R; Mrksich, M.; Oyelere, A. K. (2015) In Vitro Histone Deacetylase Activity Screening: Making a Case for Better Assays. Book Chapter, Epigenetic Technological Applications. Chapter 15, Y. G. Zheng (Ed.), Elsevier, Inc.
  16. Jiang, L.; Watkins, D.; Jin, Y.; Gong, C.; King, A.; Washington, A. Z.; Green, K. D.; Garneau-Tsodikova, S.; Oyelere, A. K.; Arya, D. P. Rapid Synthesis, RNA Binding, and Antibacterial Screening of a Peptidic-Aminosugar (PA) Library. ACS Chem. Biol. 2015, 10, 1278−1289.
  17. Washington, A. Z.; Benicewicz, D. B.; Canzoneri, J. C.; Fagan, C. E.; Mwakwari, S. C.; Maehigashi, T.; Dunham, C. M.; Oyelere, A. K. Macrolide-Peptide Conjugates as Probes of the Path of Travel of the Nascent Peptides through the Ribosome. ACS Chem. Biol. 2014, 9, 2621−2631.
  18. Sodji, Q.; Patil, V.; Jain, S.; Kornacki, J. R.; Mrksich, M.; Tekwani, B. L.; Oyelere, A. K. The antileishmanial activity of isoforms 6- and 8-selective histone deacetylase inhibitors. Med. Chem. Lett. 2014, 24, 4826–4830.
  19. Dreaden, E.C.; Raji, I.O.; Austin, L.A.; Fathi, S.; Mwakwari, S.C.; Humphries IV, W.H.; Kang, B.; Oyelere, A.K.; El-Sayed, M.A. P-glycoprotein-Dependent Trafficking of Nanoparticle-Drug Conjugates. Small 2014, 10, 1719–1723. [Featured in Materials Views, June 2014 http://www.materialsviews.com/highlight-on-p-glycoprotein-dependent-trafficking-of-nanoparticle-drug-conjugates/].
  20. Sodji, Q.; Patil, V.; Kornacki, J.; Mrksich, M.; Oyelere, A. K. Synthesis and Structure−Activity Relationship of 3‑Hydroxypyridine-2-thione-Based Histone Deacetylase Inhibitors. Med. Chem. 2013, 56, 9969−9981.
  21. Gryder, B. E.; Akbashev, M. J.; Rood, M. K.; Raftery, E. D.; Meyers, W. M.; Dillard, P.; Khan, S.; Oyelere, A. K. Selectively Targeting Prostate Cancer with Antiandrogen Equipped Histone Deacetylase Inhibitors. ACS Chem. Biol. 2013, 8, 2550−
  22. Gryder, B. E.; Rood, M. K.;  Johnson, K. A.;  Patil, V.;  Raftery, E. D.;  Yao, L-P. D.; Rice, M.; Azizi, B.; Doyle, D.; Oyelere, A. K. Histone Deacetylase Inhibitors Equipped with Estrogen Receptor Modulation Activity. Med. Chem. 2013, 56, 5782−5796. [Featured in Science-Business eXchange;  SciBX 6(29); doi:10.1038/scibx.2013.749. http://www.nature.com/scibx/journal/v6/n29/pdf/scibx.2013.749.pdf?WT.ec_id=SCIBX-20130801].
  23. Guerrant, W.; Patil, V.; Canzoneri, J.; Yao, L. P.; Hood, R.; Oyelere, A. K. Dual-acting histone deacetylase-topoisomerase I inhibitors. Med. Chem. Lett. 2013, 23, 3283–3287.
  24. Patil, V.; Sodji, Q.; Kornacki, J.; Mrksich, M.; Oyelere, A. K. 3-Hydroxypyridin-2-thiones as a novel zinc binding group for selective HDAC inhibition. Med. Chem. 2013, 56, 3492−3506.
  25. Patil, V.; Canzoneri, J. C.; Samatov, T. R.; Lührmann, R.; Oyelere, A. K. Molecular architecture of zinc chelating small molecules that inhibit spliceosome assembly at an early stage. RNA 2012, 18, 1605-1611.
  26. Dreaden, E. C.; Gryder, B. E.; Austin, L. A.; Tene Defo, B. A.; Hayden, S. C.; Pi, M.; Quarles, L. D.; Oyelere, A. K.; El-Sayed, M. A. Antiandrogen Gold Nanoparticles Dual-Target and Overcome Treatment Resistance in Hormone-Insensitive Prostate Cancer Cells. Bioconjugate Chem. 2012, 23, 1507-1512. [Most Read in Q3 – Bioconjugate Chemistry; Featured in Prostate Cell News, July 2012].
  27. Dreaden, E. C.; Mwakwari, S. C.; Austin, L. A.; Kieffer, M. J.; Oyelere, A. K.; El-Sayed, M. A. Small Molecule-Gold Nanorod Conjugates Selectively Target and Induce Macrophage Cytotoxicity towards Breast Cancer Cells. Small 2012, 8, 2819-2822.
  28. Gryder, B.; Sodji, H.; Oyelere, A. K. Targeted Cancer Therapy: Giving Histone Deacetylase Inhibitors All They Need to Succeed. Future Med. Chem. 2012, 4, 505-524.
  29. Guerrant, W.; Patil, V.; Canzoneri, J. C.; Oyelere, A. K. Dual Targeting of Histone Deacetylase and Topoisomerase II with Novel Bifunctional Inhibitors. Med. Chem. 2012, 55, 1465−1477.
  30. Gryder, B.; Guerrant, W.; Chen, C. H.; Oyelere, A. K. Oxathiazole-2-one derivative of bortezomib: Synthesis, stability and proteasome inhibition activity. Med. Chem. Commun. 2011, 2, 1083–1086.
  31. Huang, X.; Kan, B.; Qian, W.; Chen, P. C.; Oyelere, A. K.; El-Sayed, I. H.; El-Sayed, M. A. Comparative Studies of Photodestruction of Cancer Cells with Gold Nanoparticles: in the Cytoplasm or in the Nucleus and by using Pulsed or Continuous Wave Laser. Biomed. Optics 2010, 15, 058002.
  32. Mwakwari, S. C.; Guerrant, W.; Patil, V.; Khan, S. I.; Tekwani, B. L.; Gurard-Levin, Z. A.; Mrksich, M.; Oyelere, A. K. Nonpeptide Macrocyclic Histone Deacetylase (HDAC) Inhibitors Derived from Tricyclic Ketolide. Med. Chem. 2010, 53, 6100–6111.
  33. Mwakwari, S. C.; Patil, V.; Guerrant, W.; Oyelere, A. K. Macrocyclic Histone Deacetylase (HDAC) Inhibitors. Top. Med. Chem. 2010, 10, 1423-1440.
  34. Oyelere, A. K. Macrocycles in Medicinal Chemistry and Drug Discovery (Editorial). Top. Med. Chem. 2010, 10, 1359-1360.
  35. Basu, S.; Oyelere, A.K., (2010),”The Application of Recombinant DNA Technology in Medicinal Chemistry and Drug Discovery”, Burger’s Medicinal Chemistry, Drug Discovery and Development, 7th Edition, Vol 1, Chapter 14, D. J. Abraham & D. P. Rotella (Ed.), John-Wiley.
  36. Guerrant, W.; Mwakwari, S. C.; Chen, P. C.; Khan, S. I.; Tekwani, B. L.; Oyelere, A. K. A Structure Activity Relationship Study of the Antimalarial and Antileishmanial Activities of Non-peptide Macrocyclic Histone Deacetylase Inhibitors. ChemMedChem 2010, 5, 1232–1235.
  37. Patil, V.; Guerrant, W.; Chen, P. C.; Gryder, B.; Benicewicz, D. B.; Khan, S. I.; Tekwani, B. L.; Oyelere, A. K. Antimalarial and Antileishmanial Activities of Histone Deacetylase (HDAC) Inhibitors with Triazole-Linked Cap Group. Med. Chem. 2010, 18, 415–425.
  38. Dreaden, C.; Mwakwari, S. C.; Sodji, Q. H.; Oyelere, A. K.; El-Sayed, M. A. Tamoxifen−Poly(ethylene glycol)−Thiol Gold Nanoparticle Conjugates: Enhanced Potency and Selective Delivery for Breast Cancer Treatment. Bioconjugate Chem. 2009, 20, 2247–2253.
  39. Canzoneri, J. C.; Chen, P. C.; Oyelere, A. K. Design and Synthesis of Novel Histone Deacetylase Inhibitor Derived from Nuclear Localization Signal Peptide. Med. Chem. Lett. 2009, 19, 6588–6590.
  40. Oyelere, A. K.; Chen, P. C.; Guerrant, W.; Mwakwari, S. C.; Hood, R.; Zhang, Y.; Fan, Y. Nonpeptide Macrocyclic Histone Deacetylase (HDAC) Inhibitors. Med. Chem. 2009, 52, 456-468.
  41. Canzoneri, J. C.; Oyelere, A. K. Interaction of Anthracyclines with Iron Responsive Element mRNAs. Nucleic Acids Res. 2008, 36, 6825–6834.
  1. Chen, P. C.; Mwakwari, S.; Oyelere, A. K. Gold Nanoparticles – From Nanomedicine to Nanosensing. Nanotechnology, Science and Applications, 2008, 1, 45-66.
  2. Chen, P. C.; Patil, V.; Guerrant, W.; Green, P.; Oyelere, A. K. Synthesis and Structure-Activity Relationship of Histone Deacetylase (HDAC) Inhibitors with Triazole-Linked Cap Group. Med. Chem. 2008, 16, 4839–4853. [Ranked # 4 among top 25 hottest articles in Bioorg Med Chem for the 2nd quarter of 2008. Source: http://top25.sciencedirect.com/subject/chemistry/6/journal/bioorganic-medicinalchemistry/09680896/archive/18/].
  3. Oyelere, A. K.; Chen, P. C.; Huang, X.; El-Sayed, I. H.; El-Sayed, M. A. Peptide-Conjugated Gold Nanorods for Nuclear Targeting. Bioconjugate Chem. 2007, 18, 1490-1497 [One of the most-accessed articles published in Bioconjugate Chemistry in the 3rd quarter of 2007, Source: http://pubs.acs.org/journals/bcches/promo/most/most_accessed /index.html; Editor selected paper in imaging representing high quality, peer reviewed research published in Bioconjugate Chemistry].
  1. Chen, P. C.; Wharton, R. E.; Patel, P. A.; Oyelere, A. K. Direct Diazo-Transfer Reaction on β-lactam: Synthesis and Preliminary Biological Activities of 6-Triazolylpenicillanic Acids. Med. Chem. 2007, 15, 7288-7300.
  2. Oyelere, A. K.; Chen, P. C.; Yao, L. P.; Boguslavsky, N. Heterogeneous Diazo-transfer Reaction: A Facile Unmasking of Azide Groups on Amine Functionalized Insoluble Supports for Solid Phase Synthesis. Org. Chem. 2006, 71, 9791-9796.

 

Publications from research prior to Georgia Tech

  1. Zhou, J.; Bhattacharjee, A.; Chen, S.; Chen, Y.; Duffy, E.; Farmer, J.; Goldberg, J.; Hanselmann, R.; Ippolito, J. A.; Lou, R.; Orbin, A.; Oyelere, A.; Salvino, J.; Springer, D.; Tran, J.; Wang, D.; Wu, Y.; Johnson, G. Design at the atomic level: Design of biaryloxazolidinones as potent orally active antibiotics. Med. Chem. Lett. 2008, 18, 6179-6183.
  2. Zhou, J.; Bhattacharjee, A.; Chen, S.; Chen, Y.; Duffy, E.; Farmer, J.; Goldberg, J.; Hanselmann, R.; Ippolito, J. A.; Lou, R.; Orbin, A.; Oyelere, A.; Salvino, J.; Springer, D.; Tran, J.; Wang, D.; Wu, Y.; Johnson, G. Design at the atomic level: Design of biaryloxazolidinones as potent orally active antibiotics. Med. Chem. Lett. 2008, 18, 6175–6178.
  3. Basu, S.; Oyelere, A.K., (2003),”The Application of Recombinant DNA Technology in Medicinal Chemistry and Drug Discovery”, Burger’s Medicinal Chemistry, Drug Discovery and Development, 6th Edition, Vol 2, Chapter 4, 82-113, D. Abraham (Ed.), John-Wiley.
  4. Cho, H.D.; Oyelere, A.K.; Strobel, S.A; Weiner, A. M. Use of nucleotide analogs by the CCA-adding enzyme (tRNA nucleotidyltransferase): deciphering the basis for nucleotide selection RNA 2003, 9, 970-981.
  5. Strobel, S.A.; Jones, F.D.; Oyelere, A.K.; Ryder, S.P. Biochemical detection of adenosine and cytidine ionisation within RNA by interference analysis. Nucleic Acids Res. Suppl. 2003, 3, 229-230.
  6. Oyelere, A. K.; Kardon, J. R.; Strobel, S. A. pKa Perturbation in Genomic Hepatitis Delta Virus Ribozyme Catalysis Evidenced by Nucleotide Analogue Interference Mapping Biochemistry 2002, 41, 3667-3675.
  7. Ryder, S.P.; Oyelere, A.K.; Padilla, J.; Klostermeier, D.; Millar, D.P.; Strobel, S.A. A catalytically significant adenosine ionization within the hairpin ribozyme active site, RNA 2001, 7, 1454-1463.
  8. Oyelere, A.K.; Strobel, S.A. Site Specific incorporation of 6-azauridine into the genomic HDV ribozyme active site, Nucleosides & Nucleotides 2001, 20, 1851-1858.
  9. Oyelere, A.K.; Strobel, S.A. Biochemical detection of cytidine protonation within RNA.  Amer. Chem. Soc. 2000, 42, 10259-10267.
  10. Szewczak, A.A.; Ortoleva-Donnelly, L.; Zivarts, M.V.; Oyelere, A.K.; Katzantsev, A.V.; Strobel, S.A. An important Base Triple Anchors the Substrate Helix Recognition Surface within the Tetrahymena Ribozyme Active Site, Natl. Acad. Sci. USA 1999, 96, 11183-1188.
  11. Oliver, J.S.; Oyelere, A.K. Efficient Preparation of Dinucleoside Phosphates with N-FMOC Amino Acid Fluorides, Tetrahedron Lett. 1997, 38, 4005-4008.
  12. Oliver, J.S.; Oyelere, A., Aminoacylation of Nucleosides with FMOC Amino Acid Fluorides, Org. Chem. 1996, 61, 4168-4171.

 

Patents and Invention Disclosures – Application and Issued Patents (16 issued patents, and over 80 applications. Representative examples are given below)

  1. Oyelere, A.K.; Tapadar, S.; Gaul, D. Hydantoin-derived Histone Deacetylase (HDAC) Inhibitors and Methods of Making and Using Thereof. PCT WO. 2017/120328 A1
  2. Zhou, J.; Bhattacharjee, A.; Chen, S.; Chen, Y.; Farmer, J.J.; Goldberg, J.A.; Hanselmann, R.; Lou, R.; Orbin, A.; Oyelere, A.K.; Salvino, J.M.; Springer, D.M.; et al Biaryl heterocyclic compounds and methods of making and using the same. US Patent 2017/9550783 B2 (Issued Patent)
  3. Oyelere, A. K.; Gryder, B. Histone Deacetylase (HDAC) Inhibitors Targeting Prostate Tumors and Methods of Making and Using Thereof. US Patent 2015/9139565 B2 (Issued Patent)
  4. Steitz, T.A.; Moore, P.B.; Sutcliffe, J.A.; Oyelere, A.K.; Ippolito, J.A. Ribosome structure and protein synthesis inhibitors. US Patent 2014/8912150 B2 (Issued Patent)
  5. Oyelere, A.K.; Tapadar, S. Non-Peptide Macrocyclic Histone Deacetylase (HDAC) Inhibitors and Methods of Making and Using Thereof. US Patent 2014/8871728 B2 (Issued Patent)
  6. Farmer, J.J.; Bhattacharjee, A.; Chen, Y.; Goldberg, J.A.; Ippolito, J.A.; Kanyo, Z.F.; Lou, R.; Oyelere, A.K.; Sherer, E.C.; Sutcliffe, J.A.; et al Macrocyclic Compounds and Methods and Methods of Making and Using the Same. US Patent 2014/8841263 B2 (Issued Patent)
  7. Steitz, T.A.; Moore, P.B.; Sutcliffe, J.A.; Oyelere, A.K.; Ippolito, J.A. Ribosome structure and protein synthesis inhibitors. US Patent 2013/8470990 B2 (Issued Patent)
  8. Farmer, J.J.; Bhattacharjee, A.; Chen, Y.; Goldberg, J.A.; Ippolito, J.A.; Kanyo, Z.F.; Lou, R.; Oyelere, A.K.; Sherer, E.C.; Sutcliffe, J.A.; et al Macrocyclic Compounds and Methods and Methods of Making and Using the Same. US Patent 2012/8202843 B2 (Issued Patent)
  9. Oyelere, A.K. Non-Peptide Macrocyclic Histone Deacetylase (HDAC) Inhibitors and Methods of Making and Using Thereof. US Patent 2012/8188054 B2 (Issued Patent)
  10. Gryder, B.; Oyelere, A. K. Histone Deacetylase (HDAC) Inhibitors Targeting Prostate Tumors and Methods of Making and Using Thereof. WO2012 /050868A1
  11. Oyelere, A. K.; El-Sayed, M. A.; Dreaden, C. Targeted Delivery of Nanoparticles. US Patent 2011/0077581 A1
  12. Steitz, T.A.; Moore, P.B.; Sutcliffe, J.A.; Oyelere, A.K.; Ippolito, J.A. Ribosome structure and protein synthesis inhibitors. US Patent 2010/7666849 B2 (Issued Patent)
  13. Oyelere, A.K., Non-Peptide Macrocyclic Histone Deacetylase (HDAC) Inhibitors and Methods of Making and Using Thereof. US Patent 2010/0197622A1
  14. Zhou, J.; Bhattacharjee, A.; Chen, S.; Chen, Y.; Farmer, J.J.; Goldberg, J.A.; Hanselmann, R.; Lou, R.; Orbin, A.; Oyelere, A.K.; Salvino, J.M.; Springer, D.M.; et al Biaryl heterocyclic compounds and methods of making and using the same. US Patent 2008/7456206 B2 (Issued Patent)
  15. Wang, D.; Sutcliffe, J.A.; Oyelere, A.K.; McConnell, T.S.; Ippolito, J.A.; Abelson, J.N.; Springer, D.M.; et al Bifunctional Heterocyclic compounds and methods of making and using same. US Patent 2008/7335753 B2 (Issued Patent)
  16. Wang, D.; Sutcliffe, J.A.; Oyelere, A.K.; McConnell, T.S.; Ippolito, J.A.; Abelson, J.N.; Springer, D.M.; et al Bifunctional Heterocyclic compounds and methods of making and using same. US Patent 2006/7091196 B2 (Issued Patent)
  17. Chen, S.; Zhou, J.; Wu, Y.; Wang, D.; Salvino, J.M.; Oyelere, A.K.; Lou, R. Halogenated Biaryl Heterocyclic compounds and methods of making and using the same. US Patent 2006/7129259 B2 (Issued Patent)
  18. Oyelere, A.K.; Farmer, J.J. Bifunctional Macrolide Heterocyclic compounds and methods of making and using same. EP. 2006/1682563 A1
  19. Oyelere, A.K.; Goldberg, J.A.; Orbin, A.; Salvino, J.M.; Zhou, J. Biaryl heterocyclic amines, amides and sulfur-containing compounds and methods of making and using the same. EP. 2006/1664001 A2
  20. Lou, R.; Zhou, J.; Bhattacharjee, A.; Chen, S.; Chen, Y.; Farmer, J.; Goldberg, J.A.; Hanselmann, R.; Orbin, A.; Oyelere, A.K.; et al Biaryl heterocyclic compounds and methods of making and using the same. US 2006/7148219 B2 (Issued Patent)
  21. Lou, R.; Zhou, J.; Bhattacharjee, A.; Chen, S.; Chen, Y.; Farmer, J.; Goldberg, J.A.; Hanselmann, R.; Orbin, A.; Oyelere, A.K.; et al Biaryl heterocyclic compounds and methods of making and using the same. US 2005/6969726B2 (Issued Patent)
  22. Oyelere, A.K.; Goldberg, J.A.; Orbin, A.; Salvino, J.M.; Zhou, J. Biaryl heterocyclic amines, amides and sulfur-containing compounds and methods of making and using the same. PCT WO 2005/012270 A2. [One of the most requested chemistry and related science patent families by researchers using CAS electronic products in 3Q-2005, Source: http://www.cas.org/spotlight/rlist3q05p/rlist3q05p.html]
  23. Farmer, J.J.; Goldberg, J.A.; Oyelere, A.K.; Salvino, J.M.; Springer, D.M.; Tran, J. Bifunctional Macrolide Heterocyclic compounds and methods of making and using same. PCT 2005/049632 A1
  24. Abelson, J.N.; Lou, R.; Oyelere, A.K.; Salvino, J.M.; et al Bifunctional Heterocyclic compounds and methods of making and using same. CA 2004/2500158 A1
  25. Steitz, T.A.; Moore, P.B.; Ban, N.; Nissen, P.; Hansen, J.; Sutcliffe, J.A.; Oyelere, A.K.; Ippolito, J.A. Ribosome structure and protein synthesis inhibitors. EP 1308457 A1